Buy Kisspeptin-10: The Ultimate Guide to the KISS1 Neuropeptide
If you are looking to buy Kisspeptin-10 for your laboratory or clinical research, understanding the profound biological significance of this peptide is essential. Kisspeptin-10 (also known as Metastin 45-54) is a potent, truncated decapeptide derived from the KISS1 gene. It serves as the primary endogenous ligand for the G protein-coupled receptor GPR54 (Kiss1R), acting as the “master switch” for the human reproductive system.
What is Kisspeptin-10?
Kisspeptin-10 is the shortest biologically active fragment of the kisspeptin protein family. Despite its smaller size compared to Kisspeptin-54, it retains full intrinsic bioactivity and high affinity for the Kiss1R receptor.
Researchers who buy Kisspeptin-10 typically focus on its role in the Hypothalamic-Pituitary-Gonadal (HPG) axis. It is secreted by neurons in the arcuate nucleus and the preoptic area of the hypothalamus, where it stimulates the pulsatile release of Gonadotropin-Releasing Hormone (GnRH).
Key Research Benefits and Mechanism of Action
When you incorporate high-purity Kisspeptin-10 into your study, you are exploring a peptide with diverse physiological impacts:
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Hormonal Regulation: Kisspeptin-10 is the most potent known stimulator of GnRH. This stimulation leads to a rapid increase in Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), subsequently elevating endogenous testosterone and estrogen levels.
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Reproductive Health Research: It is widely studied for its potential in treating Hypogonadotropic Hypogonadism (HH), delayed puberty, and various forms of infertility.
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Psychosexual Studies: Recent clinical trials suggest Kisspeptin-10 may modulate brain pathways associated with sexual arousal, attraction, and mood, independent of its effect on testosterone.
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Metastasis Suppression: Originally discovered as “Metastin,” research continues into how Kisspeptin-10 can inhibit the migration and invasion of certain cancer cells, particularly in melanoma and breast cancer models.
Product Specifications
To ensure the integrity of your data, always verify the technical specifications before you buy Kisspeptin-10:
| Attribute | Specification |
| Molecular Formula | $C_{63}H_{78}N_{18}O_{13}$ |
| Molecular Weight | 1302.44 g/mol |
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| Purity | ≥98% (HPLC tested) |
| Format | Lyophilized White Powder |
| Solubility | Soluble in Water or DMSO |
Storage and Handling
To maintain the stability of the peptide after you buy Kisspeptin-10:
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Long-term Storage: Store the lyophilized powder at -20°C or -80°C.
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Reconstitution: Once reconstituted, use sterile bacteriostatic water or phosphate-buffered saline (PBS).
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Avoid Degradation: Aliquot the solution to avoid repeated freeze-thaw cycles, which can denature the peptide structure.
Why Buy Kisspeptin-10 for Your Study?
As of 2026, Kisspeptin-10 remains at the forefront of endocrinology and longevity research. Its ability to restore natural hormonal pulses without the “shutdown” effect seen in traditional hormone replacement therapies makes it a primary candidate for future therapeutic breakthroughs.



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